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Biocompatibility of niobium titanium in orthopedic surgery

Niobium titanium alloy has excellent biocompatibility in orthopedic surgery, which is mainly reflected in the following aspects:

Definition of biocompatibility
Biocompatibility refers to the tolerance of various biological, physical and chemical reactions produced by the interaction between materials and organisms. For materials implanted in the human body, good biocompatibility means that they will not cause toxicity or adverse reactions to surrounding tissues.

Cellular response
Niobium titanium alloy can effectively promote the adhesion, growth and differentiation of osteoblasts. When niobium titanium alloy is implanted in bone tissue, biological macromolecules in blood and tissue fluid, such as fibronectin and osteonectin, are adsorbed on the surface of the material. These macromolecules promote cell migration and proliferation, thereby accelerating the bone integration process.

Elastic modulus
Niobium titanium alloy has a lower elastic modulus, which is closer to natural bone (about 5-30 GPa), which helps to reduce the "stress shielding" effect and reduce the mechanical incompatibility between the implant and the surrounding bone tissue, thereby reducing complications such as bone resorption and atrophy.

Corrosion resistance
Niobium-titanium alloy exhibits excellent corrosion resistance in physiological environments, which means that it is not easy to degrade during long-term use in the body, thereby reducing the risk of complications such as infection.

Adaptability
Since niobium-titanium alloy does not contain toxic elements (such as aluminum and vanadium), it has higher biosafety and can effectively avoid inflammatory reactions or other health problems caused by the release of harmful ions from the material.

In summary, the superior biocompatibility of niobium-titanium alloy in orthopedic surgery makes it an ideal implant material that can effectively promote bone healing and reduce postoperative complications.